Some mfgs have tables on their website indicating different loads for different inflation rates for certain tires they offer, implying that those particular tires can be run at a lower pressure if the load permits. I understand that all others should be run at or very near the mfgs rated max.
I run mine at or near the manufacturer's recommended maximum pressure. This tends to eliminate improper wear or excessive accumulation of heat. If the trailer rides too hard for the rig, then I suspect the springs/trailer may be mismatched to the load. I was guilty of this once when I thought I would get more wear out of an overly heavy trailer. I did, but at the expense of beating the boat, motor, decoys, gear, etc. nearly to pieces. For the second boat and trailer, I selected a trailer with a more suitable load rating AND a torsion axle. The thing goes down the road like a baby carriage. Stacked decoys won't even topple over.