I have one - from IceCo. Bought it for a long hunting road trip to S Texas. Also have their small companion battery. For the 10 days, the icebox was always plugged into the battery, which remained plugged into a 12v outlet. Thus the running vehicle ran the icebox but when shut off the battery took over. With at least a couple hours on the road each day, the battery stayed topped up enough to run the box overnight and during hot mornings/afternoons in the field. It was great never needing to refresh ice for food and drinks on the way and beer while there... then cranked it down to freezer mode for getting birds back to NC (I'd frozen birds after cleaning them in TX).
For camping or periods of being in 1 place for several days and not getting the battery charged while driving, you'd need to have a larger battery and/or solar.
Getting ready to load mine up for a trip to Nashville. It's also come in handy as an extra fridge for gatherings. We had lots of family in for Thanksgiving - I plugged it in (ac) and left it on the porch. A great place for all the extras needing refrigeration.
Wish I'd bought one sooner.