There is an "S" and an "R" strain identified serologically. One is more virulent than the other. The more virulent strain appears to center in the lungs, based on limited data. Because testing and screening ramp-up was so horribly botched at the Federal level. much of the modeling and mapping, with concomitant adjustments in healthcare resource allocations and containment focus has been done in a scattershot effort. Not a good time to be living in urbania.
https://www.nejm.org/doi/full/10.1056/NEJMoa2002032
There was a pandemic rapid response initiative put together in the Obama administration years in response to the Ebola outbreak. DJT administration dismantled the program in 2018 and repositioned much of the military's resources and personnel that were tied to this. Protocols established by them are just now being dusted-off and enacted.
Regeneron has a novel in-house mouse population that they developed in response to the Ebola outbreaks. Their strain of mice contains an inserted human genome that enables them to be a near-mimic of the human immune system response. Cohorts are currently being exposed to a variety of non-virulent antigens that will likely induce antibody production. Antibody titer production peaks are being tracked for each antigen agent. Those that elicit top tier antibody production values will be compared, with one or two final choices established to produce an antibody "cocktail" in injectable form for use in aiding those patient populations at highest risk (compromised immune system di
sses such as Type-1 diabetes, Lupus,RA, asthma, ciliac disease, etc.) of responding to virus attack and fulminant infection.
https://www.yahoo.com/...ctive-114020934.html
New England Journal of Medicine reported a virus fomite transmission and aerosol risk determination study this week. Covid-19 can survive up to 72 hours on a surface like stainless steal with lessened of an interval of viability on plastic. Aerosol transmission is low risk, with viral particles viable for around three hours, but not being capable of distribution distances common with some flu viruses of 50 feet or more when dispersed by cough or sneeze.
Still, just don't get the whole TP hoarding idea...
My wife is a vet. tech. Their clinic has now gone to having their clients wait in the cars, cellphones in hand, for notification to enter and be placed in an exam room. we are usually entering the secondary peak in the annual flu cycle, caused by the return north of the "Snow Birds". Thankfully for her, and their clients they are working out of a two month old facility with updated air handling and filtration systems, in-floor heating, and one of the most fascinating water treatment set-ups I have ever seen, since the clinic is
drawing wellwater...massive three stage filtration and three day storage capacity. There is a coronavirus vaccine for dogs.
FDA approved States to develop their own in-house tests yesterday. Downside is that swab availability and production and shipping, via supply chain is woefully inadequate to keep up with national demand levels.
My internal medicine doctor is John Hopkins trained, former Oncologist/Haemotologist. He is 72, has ciliac disease, and is at high-risk, partially because he just returned to work a couple of months ago from having his leg re-broken and reset, following a emergency surgery and months long "sentence" in a nursing home, prior returning home to our regional medical facility to repair the compound fracture in British Columbia when he fell off a glacier tele-skiing via helicopter drop-off. He is truly torn as he weighs his inherent concern and obligation to his patient population against his personal risks via age, background health status level, and compromised immune system.
Our managed care dominated, too deep in administrative staff and layers of assessment of expenditure costs/profitability comparisons, is not equipped to handle this challenge, should it surge exponentially nationwide. Pray for the line-staff healthcare providers and workers. We can't even standardize care and enact HEDIS guidelines for consistent management of CAD and CHF, two of the big dollar healthcare vacuum cleaners!
IF this is not a seasonal virus, ebbing when humidty and temperatures elevate in spring and early summer, there is the real risk of circular reinfection, most likely in the far east , such as China. Vietnam, India at they try to recover production capacity and the economy. The good news is that the Chinese have demonstrated a high level of nationalism within their population, at least in the first exposure and proliferation cycle.
https://www.yahoo.com/...ctive-114020934.html
https://www.nejm.org/doi/full/10.1056/NEJMoa2002032
There was a pandemic rapid response initiative put together in the Obama administration years in response to the Ebola outbreak. DJT administration dismantled the program in 2018 and repositioned much of the military's resources and personnel that were tied to this. Protocols established by them are just now being dusted-off and enacted.
Regeneron has a novel in-house mouse population that they developed in response to the Ebola outbreaks. Their strain of mice contains an inserted human genome that enables them to be a near-mimic of the human immune system response. Cohorts are currently being exposed to a variety of non-virulent antigens that will likely induce antibody production. Antibody titer production peaks are being tracked for each antigen agent. Those that elicit top tier antibody production values will be compared, with one or two final choices established to produce an antibody "cocktail" in injectable form for use in aiding those patient populations at highest risk (compromised immune system di
sses such as Type-1 diabetes, Lupus,RA, asthma, ciliac disease, etc.) of responding to virus attack and fulminant infection.
https://www.yahoo.com/...ctive-114020934.html
New England Journal of Medicine reported a virus fomite transmission and aerosol risk determination study this week. Covid-19 can survive up to 72 hours on a surface like stainless steal with lessened of an interval of viability on plastic. Aerosol transmission is low risk, with viral particles viable for around three hours, but not being capable of distribution distances common with some flu viruses of 50 feet or more when dispersed by cough or sneeze.
Still, just don't get the whole TP hoarding idea...
My wife is a vet. tech. Their clinic has now gone to having their clients wait in the cars, cellphones in hand, for notification to enter and be placed in an exam room. we are usually entering the secondary peak in the annual flu cycle, caused by the return north of the "Snow Birds". Thankfully for her, and their clients they are working out of a two month old facility with updated air handling and filtration systems, in-floor heating, and one of the most fascinating water treatment set-ups I have ever seen, since the clinic is
drawing wellwater...massive three stage filtration and three day storage capacity. There is a coronavirus vaccine for dogs.
FDA approved States to develop their own in-house tests yesterday. Downside is that swab availability and production and shipping, via supply chain is woefully inadequate to keep up with national demand levels.
My internal medicine doctor is John Hopkins trained, former Oncologist/Haemotologist. He is 72, has ciliac disease, and is at high-risk, partially because he just returned to work a couple of months ago from having his leg re-broken and reset, following a emergency surgery and months long "sentence" in a nursing home, prior returning home to our regional medical facility to repair the compound fracture in British Columbia when he fell off a glacier tele-skiing via helicopter drop-off. He is truly torn as he weighs his inherent concern and obligation to his patient population against his personal risks via age, background health status level, and compromised immune system.
Our managed care dominated, too deep in administrative staff and layers of assessment of expenditure costs/profitability comparisons, is not equipped to handle this challenge, should it surge exponentially nationwide. Pray for the line-staff healthcare providers and workers. We can't even standardize care and enact HEDIS guidelines for consistent management of CAD and CHF, two of the big dollar healthcare vacuum cleaners!
IF this is not a seasonal virus, ebbing when humidty and temperatures elevate in spring and early summer, there is the real risk of circular reinfection, most likely in the far east , such as China. Vietnam, India at they try to recover production capacity and the economy. The good news is that the Chinese have demonstrated a high level of nationalism within their population, at least in the first exposure and proliferation cycle.
https://www.yahoo.com/...ctive-114020934.html
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